diff --git a/Formula/molecule.rb b/Formula/molecule.rb
index 970924f11e..23da9b3746 100644
--- a/Formula/molecule.rb
+++ b/Formula/molecule.rb
@@ -5,7 +5,7 @@ class Molecule < Formula
   homepage "https://molecule.readthedocs.io"
   url "https://files.pythonhosted.org/packages/8d/51/a691f91a829e0be54c8d898ece232c723936faa408496e8ac87f32846bea/molecule-2.20.1.tar.gz"
   sha256 "621797c54299775f284bbb010d5bb9be485500eecaaa14a476cbc0df285d0da7"
-  revision 1
+  revision 2
 
   bottle do
     cellar :any
@@ -16,7 +16,7 @@ class Molecule < Formula
   end
 
   depends_on "openssl@1.1"
-  depends_on "python@2"
+  uses_from_macos "python@2" # Does not support Python 3
 
   # Collect requirements from:
   #  molecule
@@ -294,7 +294,6 @@ class Molecule < Formula
   end
 
   def install
-    ENV.prepend_path "PATH", Formula["python@2"].opt_libexec/"bin"
     virtualenv_install_with_resources
   end